Product Description
MP BIOMEDICAL 0219006210 - DEOXYRIBONUCLEASE I FROM BOVINE PANCREAS - DEOXYRIBONUCLEASE FROM BEEF PANCREAS, DNASE I, WAS FIRST CRYSTALLIZED BY KUNITZ. IT IS AN ENDONUCLEASE WHICH SPLITS PHOSPHODIESTER LINKAGES, PREFERENTIALLY ADJACENT TO A PYRIMIDINE NUCLEOTIDE YIELDING 5'-PHOSPHATE TERMINATED POLYNUCLEOTIDES WITH A FREE HYDROXYL GROUP ON POSITION 3'. THE AVERAGE CHAIN OF LIMIT DIGEST IS A TETRANUCLEOTIDE. DNASE I ACTS UPON SINGLE CHAIN DNA, AND UPON DOUBLE-STRANDED DNA AND CHROMATIN. IN THE LATTER CASE, ALTHOUGH HISTONES RESTRICT SUSCEPTIBILITY TO NUCLEASE ACTION, OVER A PERIOD OF TIME NEARLY ALL CHROMATIN DNA IS ACTED UPON. ACCORDING TO MIRSKY AND SILVERMAN, T - EQUAL TO C825K53-EA
MANUFACTURER:
MP BIOMEDICAL
MANUFACTURER PART NUMBER:
0219006210
UNIT OF MEASURE:
EA
QTY PER UNIT OF MEASURE:
1
COUNTRY OF ORIGIN:
UNITED STATES OF AMERICA
ORDER INCREMENT:
1
WEIGHT:
0
CONTRACTOR PART NUMBER:
2800005593
