Product Description
CAYMAN CHEMICAL 501070-480 - LEUKOTRIENE C4 ELISA KIT - LEUKOTRIENES (LTS) ARE A GROUP OF ACUTE INFLAMMATORY MEDIATORS DERIVED FROM ARACHIDONIC ACID IN EOSINOPHILS, MAST CELLS, AND MACROPHAGES. THEIR BIOSYNTHESIS PROCEEDS VIA THE 5-LIPOXYGENASE (5-LO) PATHWAY IN WHICH 5-LO CONVERTS ARACHIDONIC ACID INTO LTA4 WITH 5(S)-HPETE AS AN INTERMEDIATE. THE CONJUGATION OF GLUTATHIONE TO LTA4 RESULTS IN THE FORMATION OF LTC4, WHICH IS THEN RAPIDLY METABOLIZED TO LTD4 AND LTE4. THIS METABOLISM IS ESSENTIALLY COMPLETE WITHIN 10 MINUTES IN THE HUMAN LUNG. CAYMANS LTC4 ELISA KIT IS A COMPETITIVE ASSAY THAT CAN BE USED FOR QUANTIFICATION OF LTC4 IN CULTURE MEDIA A - EQUAL TO C790U13-EA
MANUFACTURER:
CAYMAN CHEMICAL
MANUFACTURER PART NUMBER:
501070-480
UNIT OF MEASURE:
EA
QTY PER UNIT OF MEASURE:
1
COUNTRY OF ORIGIN:
UNITED STATES OF AMERICA
ORDER INCREMENT:
1
WEIGHT:
0
CONTRACTOR PART NUMBER:
2800084864
